Sucralose: Not Such a Sweet Story

We discussed the political and health ramifications of sugar so now we can talk about its even worse counterpart, artificial sweeteners.


In our quest for a healthier lifestyle, many have fallen for the hype and turned to artificial sweeteners as an alternative to sugar. Promoted as zero-calorie options, these chemical sweeteners have gained popularity in various food and beverage products. However, scientific studies have raised concerns about the potential dangers of artificial sweeteners, such as sucralose (found in Splenda), and their impact on human health.


Understanding Artificial Sweeteners


Artificial sweeteners are sugar substitutes that provide the sweetness of sugar without the associated calorie intake. Sucralose, commonly marketed under the brand name Splenda, is one such popular artificial sweetener. It is a chlorinated derivative of sucrose and is approximately 600 times sweeter than sugar.


DNA Damage and Cellular Effects


Several studies have indicated that sucralose and other artificial sweeteners may have adverse effects on human health. A study published in the journal Mutation Research found that sucralose caused DNA damage in a dose-dependent manner in laboratory tests conducted on bacteria and human cells. DNA damage is a concerning issue, as it can lead to mutations and potentially increase the risk of cancer development.


Cancer Connections


The potential link between artificial sweeteners and cancer has been a subject of scientific investigation. A study published in the International Journal of Occupational and Environmental Health found an association between long-term sucralose consumption and an increased risk of leukemia in mice. However, it is important to note that these findings were observed in animal studies, and more research is needed to establish a direct connection between sucralose and cancer in humans.


Metabolic and Weight-Related Issues


Artificial sweeteners, including sucralose, are often used as a tool for weight management and controlling diabetes. Paradoxically, research suggests that these sweeteners may contribute to metabolic dysregulation and weight gain. A study published in the journal Cell Metabolism found that consumption of artificial sweeteners altered the gut microbiome, leading to glucose intolerance and metabolic disturbances in both mice and humans.


Neurological and Behavioral Concerns


The impact of artificial sweeteners on the brain and behavior is another area of scientific interest. Research published in the journal Trends in Endocrinology and Metabolism indicated that frequent consumption of artificial sweeteners might disrupt the reward processing pathways in the brain, potentially leading to increased cravings for sweet foods and an altered perception of satiety. Furthermore, some studies have suggested a possible association between artificial sweeteners and neurological disorders, such as migraines and seizures.


I have never gotten on the bandwagon of artificial sweeteners. Hearing the rumors that they are actually made from the chemical insecticide (ant killer) and just having a general distrust for the established information. More and more studies are confirming the same storyline, can’t trust the “professionals” when they are Rockefeller-run.


Be ever aware and mindful of your health in every aspect. Do your research and remember the establishment is not our friend. Use your buying and voting power as we have seen they are incredibly useful when exercised properly (look at Target and Budlight) Show these corporations, and their pet politicians, that they are not allowed to slowly kill us.




  1. Soffritti M, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016;22(1):7-17.
  2. Schiffman SS, et al. Sucralose, a synthetic organochlorine sweetener: overview of biological issues. J Toxicol Environ Health B Crit Rev. 2013;16(7):399-451.
  3. Suez J, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014;514(7521):181-186.
  4. Sylvetsky AC, et al. Artificial sweetener consumption is associated with increased odds of high-risk abdominal obesity in adults. Appetite. 2017;115:397-405.
  5. Yang Q. Gain weight by “going diet?” Artificial sweeteners and the neurobiology of sugar cravings: Neuroscience 2010. Yale J Biol Med. 2010;83(2):101-108.

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